Stem Cell Therapy for Ankles at RMI

If you suffer from chronic or acute ankle pain or instability due to arthritis, cartilage loss, ligament strain or tear, or tendon damage, then you may benefit from non-surgical stem cell treatments or stem cell-enhanced surgery.

Can stem cells heal ankle injuries?

Dr. Riordan has published a case study in CellR4 Repair, Replacement, Regeneration & Reprogramming on treating severe chronic Achilles tendinopathy with bone marrow aspirate concentrate (BMAC), which contains several types of stem cells known to rebuild and vascularize tissue. 10 weeks after the ultrasound-guided injections into the tendon, MRI imaging confirmed significant healing. At 32 weeks, MRI images showed nearly complete healing.

Original article: Minimally Invasive Autologous Bone Marrow Concentrate Stem Cells in the Treatment of the Chronically Injured Achilles Tendon: A Case Report

To read the 32-week follow-up letter to the CellR4 editor, click here.

University of Arkansas Volleyball Player Bounce Back After Ankle Injury

Elizabeth: “I was practicing volleyball at the University of Arkansas one day, and I came down on one of my teammates’ ankles, and I just completely blew out my ankle. Tore pretty much all of the ligaments and tendons in it, and it was just a really significant injury.

I always joke with people that my bad ankle is now my good ankle and my good ankle is now my bad ankle, because I mean it feels like a brand new ankle. Sometimes I even forget that I had the stem cells because it just feels great.”

Here’s what more RMI patients have to say:

I can run without pain. Achilles inflammation is minimal.
Ron W. - Achilles Bursitis/Tendinitis

Stem Cell-Augmented Achilles Tendon Rupture Repair Yields Excellent Results

In this study, 27 patients underwent surgery augmented with bone marrow aspirate concentrate (BMAC). 25 of these patients returned to their sport around 6 months post-treatment. Patients were walking without a boot in about 2 months and were able to participate in light activity at around 3 months. Excellent results, including no re-ruptures and early mobilization, were observed in this small cohort with open Achilles tendon repair augmented by BMAC. No adverse outcomes of biologic treatment were observed with this protocol.

Read Full Abstract…


What makes stem cell therapy at RMI different?

  • Board-certified orthopedic surgeons and interventional pain management specialists
  • Over 30 years collective experience in regenerative medicine
  • Efficient bone marrow harvesting using fluoroscopic guidance (C-Arm)
  • Bone Marrow Aspirate concentration (BMAC) with Vertical Axis Centrifuge
  • Precision injections with ultrasound and/or fluoroscopic guidance
  • Amniotic and umbilical cord tissue products developed by applied stem cell research expert, Neil H. Riordan, PA, PhD
  • Learn More…

Regenerative Medicine the Future of Interventional Orthopedics – Rudy Herrera, MD

At RMI, we are augmenting BMAC with a pliable tissue allograft (transplant) developed by Dr. Riordan. It is derived from human placental amnion, which functions as a biologic structural matrix to facilitate and enhance tissue healing and repair. It contains 108 different growth factors including more than 10 times the amount of WNT-4 and more than 60 times the amount of prostaglandin as competing products.

Prostaglandin inhibits inflammation, which occurs after injury and marks the beginning of the healing process. The faster we can tame this inflammation, the sooner the body can move on to the next phase of healing, regeneration.

WNT4 is arguably the single most important molecule required for wound healing.

For more information about BMAC and amniotic tissue products used at the Riordan Medical Institute Click Here.

Common ankle and foot conditions treated at Riordan Medical Institute (RMI):

Below are common ankle and foot conditions we treat at Riordan Medical Institute. If your condition is not listed, please contact us to see if you are a candidate.

  • Achilles’ tendon damage
  • Ankle instability
  • Arthritis
  • Chronic debris
  • Fractures: non-union or slow healing
  • Ligament strain or tear
  • Osteoarthritis
  • Peroneal tendon sprain or tear
  • Plantar fasciitis


View/download the entire chapter about stem cell therapy for orthopedic conditions from Dr. Riordan’s book

For more detailed information about our treatments, we welcome you to read/download the entire chapter on stem cell therapy for orthopedic conditions from Dr. Riordan’s new book, Stem Cell Therapy: A Rising Tide – How Stem Cells are Disrupting Medicine and Transforming Lives.  CLICK HERE (FREE PDF)

“Neil takes readers on a riveting journey through the past, present and future of stem cell therapy. His well-researched, educational and entertaining book could change your life. I highly recommend it.”Tony Robbins, NY Times #1 Bestselling Author

“100 years old will soon become the new 60. Stem cells are a key therapeutic to enable this future. Dr. Riordan’s book is your guide to why this is true and how you will benefit. A must read for anyone who cares about extending their healthy lifespan.”Peter H. Diamandis, MD; Founder, XPRIZE & Singularity University; Co-Founder, Human Longevity, Inc.; Author of NY Times Best Sellers Abundance and Bold

*Amniotic tissue is donated after normal, healthy births. Once it has been fully tested for infectious diseases, sterility and a few other things, the tissue is processed by using proprietary methods developed by Neil Riordan, PhD.